These data suggested a critical impact of KLK6 on tumor cell motility, which was further supported by an accelerated migration rate (Fig. 2B-C), as well as an induced invasion capacity in a matrigel-coated Boyden chamber assay of FaDu-shKLK6 clones as compared to FaDu-Mock controls (Fig. 2E-F). This evidence concerns the gene KLK6 and neoplasm.