Additionally, all four human breast cancer cell lines, with diverse histological staining characteristics (Supplementary Table S1), exhibited high levels of CDK11p110 expression, especially in BT-474, MCF-7, and MDA-MB-468 cells, whereas the expression of CDK11p110 was tightly regulated in the normal breast cell line (Fig. 1B). This evidence concerns the gene CDK11B and breast cancer.