To test our hypothesis, that ovarian cancer cells secrete LPI, and thus promote tumour angiogenesis in vivo via an LPI/GPR55-dependent mechanism; conditioned medium from the human ovarian cancer cell lines OVCAR-3, OVCAR-5 and COV-362 was analysed for its LPI levels and in the CAM angiogenesis model. Here, GPR55 is linked to neoplasm.