For example, based on their impact on muscular ultrastructure or their involvement in myopathies, molecular chaperones, such as TRIC (cct), αB-crystallin/HSPB5 (hsp-25), and DNAJB6 (dnj-24), were suggested to play a key role in sarcomere assembly and maintenance (Ding and Candido, 2000; Vang et al., 2005; Kim et al., 2008; Willis et al., 2009; Willis and Patterson, 2010; Garrido et al., 2012; Haslbeck et al., 2012; Sarparanta et al., 2012). This evidence concerns the gene CRYAB and myopathy.