If one compares pediatric cancers to colorectal cancer which have an incidence of 400 cases per million in the USA (Haggar and Boushey, 2009), and a bias toward particular predictive biomarkers such as KRAS or NRAS mutation (Douillard et al., 2013) the feasibility of applying this technique to colorectal and other common cancers is clear. This evidence concerns the gene KRAS and colorectal cancer.