FN1 and neoplasm: Nanoglobular Gd-DOTA conjugates [lysine dendrimers (G2 and G3) with cubic silsesquioxane cores] were attached to the peptide CLTI, which specifically binds to fibrin-fibronectin complexes that are present in the tumor extracellular matrix (Pilch et al., 2006), and were subsequently used for MRI identification of tumor tissues in female nude mice bearing MDA-MB-231 human breast carcinoma xenografts.