In the case of FGFR1OP-RET fusion, the chimeric protein found in papillary thyroid carcinomas and other myeloproliferative disorders, such as CML, chronic eosinophilic leukemia, chronic neutrophilic leukemia, polycytemia vera, PMF, essential thrombocytosis, myelodysplastic syndromes (MDS), and CMML was shown to display constitutive tyrosine kinase and transforming activity (Bossi et al., 2014). Here, RET is linked to myelodysplastic syndrome.