EGFR and glioblastoma: Analysis through The Cancer Genome Atlas (TCGA) initiative identified several subclasses of GBM, termed Proneural, Neural, Classical, and Mesenchymal, which are strongly associated with genomic abnormalities in platelet-derived growth factor receptor (PDGFR), isocitrate dehydrogenase 1 or 2 (IDH 1 or 2), epidermal growth factor receptor (EGFR), and neurofibromin 1 (NF1), respectively [2, 3].