In men, subcutaneous fat storage capacity is significantly lower, driven predominantly by differential sex hormone settings, thus with weight gain excess fat is placed more rapidly into other tissues in men, such as in intra-abdominal, perivascular, skeletal muscle, liver and pancreatic areas, the process being indicated by a rise in ALT and GGT along with dyslipidaemia [1]. The gene discussed is GPT; the disease is inherited lipid metabolism disorder.