PPARG and systemic sclerosis: In the US population, one SNP (rs10865710) located on the first intron of PPARG (Table 2) achieved uncorrected statistical significance (P = 0.010; OR = 1.52 (95% CI 1.10, 2.08) per C allele) and narrowly missed our multiple-testing-corrected significance threshold of P = 0.006 for association with SSc.