Moreover, the expressions of VEGF, MIP-2, TGF-β1, IL-6, and IL-8 were all up-regulated in GCN-MSCs and BM-MSCs by 10 % BGC-823-CM or MKN-28-CM stimulation, suggesting a converted progression suffered by MSCs from non-malignant tissues by tumor cells. The gene discussed is TGFB1; the disease is neoplasm.