HGF and cancer: Sgt1 interacts with Hsp90 and functions as a cochaperone of Hsp90.3, 6, 11, 17, 21 Sgt1 is involved in stability of Polo, Mis12 complex and Scribble that are required for centrosome maturation, proper kinetochore assembly or HGF-mediated epithelial morphogenesis, respectively.11, 17, 21 Therefore, we hypothesized that Sgt1 may be involved in stability of the oncofusion proteins that are essential for the proliferation of cancer cells.