An Hsp90 cochaperone that is overexpressed in cancers is a potential target for cancer therapy, because Hsp90 requires cochaperones to function.33 Knockdown of Cdc37 expression inhibits the growth of cancer cells and xenografts.34 Given that Sgt1 is a cochaperone of Hsp90, that Sgt1 is overexpressed in tumor cells and that decreased Sgt1 protein suppresses cellular transformation and allograft growth, we believe that Sgt1 could be a potential target for cancer therapy. The gene discussed is CDC37; the disease is neoplasm.