CAV1 and neoplasm: In more detail, our data on the enhanced growth of MPR31-4 tumors in Cav1-deficient mice corroborate earlier findings on increased growth of Lewis lung carcinoma tumors implanted to Cav1-deficient mice.45 The authors of this study attributed the higher growth rates of Lewis lung carcinoma cells on Cav1-deficient mice to increased tumor angiogenesis and decreased tumor cell death.