CAV1 and prostate cancer: Consistent with earlier findings we demonstrate that the increased expression of Cav1 in epithelial cancer cells of advanced human prostate cancer tissue specimen was paralleled by a reduction of Cav1 in the tumor stroma, which is well known to have a more reactive phenotype in advanced prostate carcinoma.67, 68, 69 However, here we show for the first time that alterations in stromal Cav1 levels did not include the tumor vasculature.