GPR65 levels also correlated with levels of two other anti-apoptotic proteins known to play important roles in CLL, Mcl-1 (r=0.4847, p=0.0010) and Bcl-xl (r=0.3411, p=0.0252), although not as strongly as with Bcl-2. This evidence concerns the gene MCL1 and B-cell chronic lymphocytic leukemia.