GPT and blood coagulation disease: Thirteen APAP overdose patients with liver function tests [ALT > 1000 U/L and evidence of coagulopathy as indicated by a prothrombin time (PT > 18 s)] were classified as “abnormal LT” while nine APAP overdose patients who had liver test (peak ALT < 100 U/L and PT < 18 s) were classified as “normal LT.” There were six healthy control patients in the study.