However, two other mutations in KCNC3, R423H and P448L do cause a very rare non-progressive early onset autosomal dominant ataxia that is sometimes associated with mild mental retardation and normal imaging, reminiscent of our case and also of the phenotype of ‘cerebral palsy’ (Waters et al., 2006; Figueroa et al., 2010, 2011). This evidence concerns the gene KCNC3 and cerebral palsy.