Strikingly, analysis of publically available CRC patient tissue data (www.oncomine.org; [26]) showed a significant down-regulation of SLC1A1 mRNA levels in CRC compared to normal tissue in 11 out of 15 datasets, while SLC1A3 expression was generally unaltered (Additional file 1: Figure S1B). The gene discussed is SLC1A1; the disease is colorectal carcinoma.