POSTN and allergic disease: Periostin has been found to be related to the physiopathology of multiple diseases such as: ankylosing spondylitis (AS) [20], idiopathic interstitial pneumonias (IIPs) [21], idiopathic pulmonary fibrosis (IPF) [22], renal inflammation and fibrosis [23], heart aging [12], cancer [24, 25], and allergic diseases (Table 1).