The differentially methylated sites found during neuronal differentiation were preferentially associated with chromatin remodeling complex biological function, an interesting finding considering the previous study where the oxidative stress present in SCZP-NPC was reverted to NPC control levels after treatment of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor [24]. The gene discussed is HDAC9; the disease is nasopharyngeal carcinoma.