BRAF and neoplasm: We also analyzed whether the amount of BRAF-mutant cfDNA correlated with discrepancies between cfDNA and tumor tissue and, indeed, patients with concordant results between cfDNA and tissue had a median of 1.99% of BRAF-mutant cfDNA compared to a median of 0.02% of BRAF-mutant cfDNA in patients with discrepant results (p = 0.001).