Of the 157 patients, 137 were tested for BRAF mutation in tumor and cfDNA samples; 38 (28%) patients had a BRAF V600 mutation in the FFPE tumor samples and 33 (24%) had BRAF V600 mutations in cfDNA from plasma, with overall agreement between testing modalities in 124 (91%) cases (kappa 0.75, SE 0.07, 95% confidence interval [CI] 0.63–0.88) with sensitivity 76% (95% CI 0.60–0.89), specificity 96% (95% CI 0.90–0.99), positive predictive value 88% (95% CI 0.72–0.97) and negative predictive value 91% (95% CI 0.84–0.96; Table 1). This evidence concerns the gene BRAF and neoplasm.