HEY1 and neuroblastoma: In the miR-659-3p-transfected NB cell lines, the expression of AKT3, BCL2, CYR61 and THSB2 was confirmed to be specifically modified by miR-659-3p mimic and inhibitor, whereas that of RNASEL was not affected by the treatment and that of HEY1 and ZNF652 occurred in the wrong direction (Figure 3).