SH2B3 and cancer: We screened the expression levels of the TSGs that were selected from the cancer gene census, and found that 2 genes, BCOR and SH2B3, showed near-complete suppression (fragments per kilobase of transcript, per million fragments sequenced (FPKM) < 0.1), whereas every NC sample had FPKM > 1 (Supplementary Figure 3A and 3B).