TFF1 and adenocarcinoma: Histological analysis using H&E staining indicated a marked increase of invasive adenocarcinoma occurrence among infected Tff1-KO mice (7 out of 21, 33%) as compared to age-matched (8–15 month old mice) uninfected Tff1-KO mice (5 out of 48, 10%), using our inventory from 2009–2014 (Figure 6D).