However, we observed equivalent percentages of pTreg cells induced in the transferred T cell population in colitis models, and also equivalent percentages of transferred control and Itgb8 KO Treg cells expressing similar levels of Foxp3, strongly indicating that induction of pTreg cells and stability of transferred Treg cells is not dependent on expression of integrin αvβ8. This evidence concerns the gene ITGB8 and colitis.