Two human tumor cell lines highly expressing EphA3 and TERT(C4-2B and HGC27 cell) and cell line that expressed little EphA3 and TERT (2BS cell) were infected with Ad-TERTp-E1A-1504, Ad-TERTp-E1A-NC, or Ad-ΔE1A-1504 or Ad-ΔE1A-NC at the indicated titers. This evidence concerns the gene EPHA3 and neoplasm.