TMEM100 and Cirrhosis: TMEM100 expression was significantly associated with cirrhosis (p = 0.03), tumor size (p < 0.001), Tumor nodule number (p < 0.001), TNM stage (p < 0.001), BCLC stage (p < 0.001), Edmondson-Steiner Stage (p = 0.002) and vein invasion (p < 0.001, Table 1), respectively.