On univariate survival analysis, cirrhosis (p = 0.012, p = 0.038), tumor nodule number (p = 0.019, p = 0.036), vein invasion (p = 0.024, p = 0.013) and TMEM100 expression (p = 0.008, p = 0.009) reached significance for overall survival (OS) and Disease-free survival (DFS), respectively (Table 2 & Table 3). Here, TMEM100 is linked to Cirrhosis.