ERBB2 and head and neck squamous cell carcinoma: Another study was performed to examine the effects of EGCG on activation of the HER2 receptor in human HNSCC and breast carcinoma cell lines and results confirmed that treatment of human HNSCC and breast carcinoma cell lines with 10 or 30 μg of EGCG causes 50% inhibition of growth, noticeably inhibiting the phosphorylation of HER2 in both cell lines [52].