EGFR and breast carcinoma: Experiment was carried out to evaluate the effects of EGCG (10–100 μg/mL) treatment on growth and invasion in a breast carcinoma cell line resistant to tamoxifen (MCF-7Tam) and parental MCF-7 and the results revealed that dose-dependent downregulation of EGFR mRNA expression and protein level occurred after 50 μg/mL EGCG treatments of MCF-7Tam cells [56].