Authors studying the effect of oxidative–antioxidative balance disorders in children with ALL on the level of extracellular cytokines IL-2, IL-4, IL-5, IL-10, TNF-α and INF-α in serum, observed increased IL-10 level, higher TNF-α, IL-4, IL-5 and INF-γ levels in children with ALL compared with healthy children [5]. The gene discussed is TNF; the disease is acute lymphoblastic leukemia.