The median baseline CXCL13 levels in the CSF samples were 972 pg/mL (IQR 213–6,870, range 134–7,140) for patients with neurosyphilis, 8,000 pg/mL (IQR 4,170–20,747; range 3,247–29,110) for patients with LNB, and 7.8 pg/mL (IQR 7.8–20.6; range 7.8–59.4) for patients with MS. Here, CXCL13 is linked to neurosyphilis.