Furthermore, we also found that E-cadherin block can also abrogate the repression of vimentin and Snail-1 mediated by RBP2 knockdown (Supplementary Figure 2d and 2e), which may be accountable for the abrogation of capacity of cell migration and stemness maintenance inhibition by RBP2 knockdown in GC cell lines. This evidence concerns the gene RBP2 and gastric cancer.