It has been widely recognized that 5–15% of the patients with FMF do not respond to colchicine.[30] We did not examine ABCB1 polymorphisms which are associated with colchicine non-responders,[31] in the present study, but six HLA-B*35:01-carriers were identified among poor responders (42.9%) giving a significant increase in the carrier frequency in comparison to colchicine responders. This evidence concerns the gene ABCB1 and familial Mediterranean fever.