Whereas, other proteins, such as LPCAT2 that is highly expressed in inflammatory cells [22], BPIFA3 that is highly expressed in lung cancer [23], PPIA that activates NFkB pathway [24], and FABP4 that has pro-angiogenic role [25], were downregulated in SBP1 overexpression xenograft tumors. This evidence concerns the gene PPIA and lung cancer.