Interestingly, mice that died within 30 h of D39 infection, had significantly higher circulating cTnI levels at 12 h and 24 h (179±23 pg/ml) than mice that survived (39±10 pg/ml) (Fig 1H) suggesting that elevated cardiac troponins in this context could be reflective of greater disease severity and worse outcomes. The gene discussed is TNNI3; the disease is infection.