We show here that injecting mice i.v. with toxin-sequestering liposomes (100 mg/kg) 30 min after injecting them with WT D39 pneumococci, resulted in a significant reduction in circulating cTnI by 12 and 24 h post-infection to levels as low as 12–15 pg/ml (Figs 1F and S1B). The gene discussed is TNNI3; the disease is infection.