Six variants within two loci reached statistical significance for the association to GDM risk after FDR multiple comparisons adjustment (Table 2): TCF7L2 (rs7901695, Q = 0.00314, OR = 2.14[1.47–3.11]; rs4506565, Q = 0.00314, OR = 2.06[1.45–2.94]; rs7903146; Q = 0.00324, OR = 2.07[1.44–2.98]; rs12243326, Q = 0.00061, OR [95%CI] = 2.89[1.85–4.52]) and KCNQ1 (rs2237892, Q = 0.007, OR = 0.58[0.43–0.78]; rs2237897, Q = 0.00314, OR = 0.54[0.40–0.72]). The gene discussed is KCNQ1; the disease is gestational diabetes.