Apart from TCF7L2 and KCNQ1, seven additional loci previously related to T2D (KLF14, HHEX, GRB14, DUSP9 and PEPD), increased BMI (FAIM2) or GDM (FTSJD1/CALB2), were nominally associated to the risk of developing GDM. The gene discussed is CMTR2; the disease is type 2 diabetes mellitus.