Among those, PSORS1 explains 50% of the genetic variance and HLA-Cw6 (specifically Cw*0602) seems to be the stronger link; however the possibility that other alleles within the same locus cosegregate with Cw*0602 cannot be ruled out, and at this time no clear role for HLA-Cw6 in the pathogenesis of psoriasis has been inferred. Here, HLA-C is linked to psoriasis.