CX3CR1 and ischemia: Stimulation of microglia also relies on TLR4 stimulation, fractalkine receptor (CX3CR1) modulation and/or reduced CD200 receptor stimulation evoked by ischemia-induced disturbance of neuron-microglia cross-talk (Lehnardt et al., 2003; Dénes et al., 2008; Dentesano et al., 2012).