As a consequence of this, all the Trf1Δ/ΔK-Ras+/G12Vp53−/− mice survived until the end point of the experiment (24 weeks post-infection), while only 50% of the Trf1+/+K-Ras+/G12Vp53−/− mice survived the same period. The gene discussed is KRAS; the disease is infection.