By blind histopathological analysis of the lungs, we confirmed that Trf1Δ/ΔK-Ras+/G12Vp53−/− lungs developed less carcinomas than Trf1+/+K-Ras+/G12Vp53−/− lungs (Supplementary Fig S2A–C). This evidence concerns the gene KRAS and carcinoma.