Moreover, a publication recently attempted to intraoviductally inject adenovirus into MUC1/KRAS/PTEN floxed mice, which resulted in high-grade endometrioid carcinoma; however, intraoviductal injections can be leaky, often infecting the ovarian surface, and as previous reports suggest, oviductal infectivity is limited in vivo and in 3D in vitro cultures [5, 7]. Here, PTEN is linked to endometrioid adenocarcinoma.