Significant differences in PRR11 expression between normal tissues and tumors were observed in esophageal squamous cell cancer (ESCC), gastric cancer (GC), colorectal cancer (CRC), pancreatic ductal cancer (PDC), and hilar cholangiocarcinoma (HC), but not in hepatocellular carcinoma (HCC) (Figure S1). The gene discussed is PRR11; the disease is hepatocellular carcinoma.