ATRX and astrocytoma (excluding glioblastoma): Consistent with our previous report, ATRX mRNA expression was significantly different in grade II-IV astrocytic tumors (Figure 1A; p < 0.0001) and reduced in grade II astrocytomas compared with in pGBMs and AAs (Figure 1A; p < 0.0001, p < 0.05, respectively).