The amount of Pim-3 mRNA associated with AGO1 was significantly higher in MiaPaca-2 and PCI55 pancreatic cancer cells transfected with miR-33a mimics than in parental cells or cells transfected with negative control mimics (cel-miR-239b) (Figure 4C). The gene discussed is AGO1; the disease is familial pancreatic carcinoma.