Full or partial methylation was detected in five renal cancer cell lines (786-0, Caki-1, Osrc-2, Kert-3 and 769P), which showed downregulated GPX3 expression, whereas only weak or no methylation was detected in the cell lines (Hek293 and HK-2) with GPX3 expression (Figure 1A). This evidence concerns the gene GPX3 and renal carcinoma.