A study conducted in FEP patients found that increased interleukin-6 (IL-6) gene expression in leukocytes correlated with smaller left hippocampal volume [53], while another study conducted in young adults with schizophrenia found a correlation between peripheral IL-6 and C-reactive protein (CRP) levels and WM diffusion [54]. The gene discussed is IL6; the disease is schizophrenia.