GABRA1 and juvenile myoclonic epilepsy: In brief, mutations in GABRA1 have been found to be linked to juvenile myoclonic epilepsy (JME) and childhood absence epilepsy (CAE); mutations on GABRB3 can cause CAE; mutant GABRG2 genes can be linked to febrile seizures (FS), CAE, Dravet syndrome (DS), or generalized epilepsy with febrile seizures plus (GEFS+).