To elucidate the mechanisms underlying the pro-tumorigenic polarization of TAMs in ovarian cancer and the role of PPARβ/δ in this context we determined the PPARβ/δ-regulated transcriptome and PPARβ/δ cistrome in ovarian carcinoma TAMs in comparison to normal human monocyte-derived macrophages (MDMs). The gene discussed is PPARD; the disease is ovarian carcinoma.