Although there is no direct data about the interaction of CXCL13 with CXCR5 in lymphoma cells of ENKTL, a previous in vitro study with AIDS-related non-Hodgkin lymphoma cell lines demonstrated migration of lymphoma cells expressing CXCR5 toward CXCL13 [27]. This evidence concerns the gene CXCL13 and non-Hodgkin lymphoma.