HNF4A and gastric cancer: As shown in Figure 6A and Figure 6B, higher protein and transcript levels of ITLN1 or HNF4α were observed in gastric cancer tissues and cell lines than those in normal gastric mucosa, while their expression levels gradually decreased along with the histological differentiation grades of gastric cancer (Figure 6C, P < 0.0001), which was in line with the results from public databases (Figure S5A, Figure S5B, and Figure S5C).