AFP and neoplasm: Univariate analysis identified the following factors as associated with higher incidence of tumor recurrence after curative hepatectomy: AFP level ≥400 ng/mL (P = 0.015), multiple tumors (P = 0.002), tumor size >5 cm (P < 0.001), BCLC B stage (P = 0.001), and major resection (P < 0.001).