In a murine model of trichomoniasis, this infection resulted in an increased incidence of septic abortions that were associated with a decreased in HO-1 expression in uterine tissues and a concomitant increase in Th17 responses as reflected by an increase in RORγt expression, a transcription factor that promotes Th17 differentiation (Woudwyk et al., 2012). The gene discussed is HMOX1; the disease is infection.