MUC16 and metastatic malignant neoplasm in the lymph nodes: When we used preoperative serum CA125 to predict only lymph node metastasis without adnexal involvement, distant metastasis and positive peritoneal cytology, the CA125 serum level of 25 U/mL was best, with 78% of sensitivity, 78% of specificity, 77.6% of false positive rate, 2.3% of false negative rate (Figure 1B).