MUC16 and metastatic malignant neoplasm in the lymph nodes: When we used preoperative serum CA125 to predict only lymph node metastasis without adnexal involvement, distant metastasis and positive peritoneal cytology, the CA125 serum level of 25 U/mL was also best, with 71.7% of sensitivity, 77.6% of specificity, 83.3% of false positive rate, 2.2% of false negative rate (Figure 2B).